A four-protein metabolon assembled by a small peptide protein creates the pentacyclic carbonate ring of aldgamycins

Organic carbonates (OCs) are a class of compounds featured by a carbonyl flanked by two alkoxy/aryloxy groups. They exist in either linear or cyclic forms, of which the majority encountered in nature adopt a pentacyclic structure. However, the enzymatic basis for pentacyclic carbonate ring formation remains elusive. Here, we reported that a four-protein metabolon (AlmUII-UV) assembled by a small peptide protein (AlmUV) appends a reactive

Comparative study on incisional complications between transumbilical single incision laparoscopic appendectomy and conventional laparoscopic appendectomy / 重庆医学

Objective To compare the difference in incisional complications between transumbilical single insicion laparoscopic appendectomy(TUSILA) and conventional laparoscopic appendectomy(CLA).Methods The incisional complications in 312 cases of TUSILA and 346 cases of CLA in the general surgery department of this hospital from January 2011 to December 29014 were retrospectively analyzed.The total occurrence rate of incision complications,incision infection rate and incision hernia occurrence rate were observed in the two groups.Results The incision complications occurrence rate,incision infection rate and incision hernia occurrence rate had no statistical difference between the TUSILA group and CLA group(P＞0.05).The univariate analysis showed that the incision infection was correlated with high BMI,complicating type 2 diabetes mellitus (T2DM) and indwelling drainage tube;the Spearman correlation analysis indicated that incision hernia was closely correlated with the incision infection(r=0.82,P＜0.05).Conclusion Compared with CLA,TUSILA does not increase the incision complications occurrence rate.

Influence of psychological communication on psychological state of elderly patients before destined operation / 中国实用护理杂志

ObjectiveTo discuss the effect of preoperative psychological communication on psychological state of elderly patients before destined operation.Methods136 cases of elderly patients underwent elective operation were divided into the observation group and the control group with 68 cases in each group,the control group was given routine nursing of general surgery,the observation group received targeted psychological communication based upon routine nursing for consecutive 3 days before surgery.The psychological state such as anxiety,depression and fear was compared between two groups.ResultsThe anxiety,depression and fear in the observation group was significantly improved compared with the control group.ConclusionsPreoperative appropriate and targeted psychological communication can alleviate the anxiety,depression and fear of the elderly patients with elective operation,and contribute to the smooth operation.